hkCP dCP STARR-Seq Track Settings

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Housekeeping and Developmental Enhancers Identified by STARR-Seq (All Expression and Regulation tracks)

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All	*Cell Line*	S2	OSC
*Reporter Type*
Housekeeping
Developmental

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	hide Configure	hkCP (S2) MACS2	RpS12 (hkCP) Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	hkCP (S2) logLR	RpS12 (hkCP) Enhancers (S2) Log Likelihood Enrichment	Schema
	hide Configure	hkCP (OSC) MACS2	RpS12 (hkCP) Enhancers (OSC) MACS2 Peaks	Schema
	hide Configure	hkCP (OSC) logLR	RpS12 (hkCP) Enhancers (OSC) Log Likelihood Enrichment	Schema
	hide Configure	eEF1delta (S2) MACS2	eEF1delta Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	eEF1delta (S2) logLR	eEF1delta Enhancers (S2) Log Likelihood Enrichment	Schema
	hide Configure	NipB (S2) MACS2	NipB Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	NipB (S2) logLR	NipB Enhancers (S2) Log Likelihood Enrichment	Schema
	hide Configure	X16 (S2) MACS2	X16 Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	X16 (S2) logLR	X16 Enhancers (S2) Log Likelihood Enrichment	Schema
	hide Configure	dCP (S2) MACS2	DSCP (dCP) Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	dCP (S2) logLR	DSCP (dCP) Enhancers (S2) Log Likelihood Enrichment	Schema
	hide Configure	dCP (OSC) MACS2	DSCP (dCP) Enhancers (OSC) MACS2 Peaks	Schema
	hide Configure	dCP (OSC) logLR	DSCP (dCP) Enhancers (OSC) Log Likelihood Enrichment	Schema
	hide Configure	pnr (S2) MACS2	pnr Enhancers (S2) MACS2 Peaks	Schema
	hide Configure	pnr (S2) logLR	pnr Enhancers (S2) Log Likelihood Enrichment	Schema

Description

These tracks show the putative housekeeping (hkCP) and developmental (dCP) enhancers identified by STARR-Seq in S2 and OSC cells. The regions that are enriched in STARR-Seq reads were identified by MACS2. The log likelihood ratio evidence tracks were also produced by MACS2.

The STARR-Seq reporters used in this study are as follows:

Reporter	Description	Reporter Type
RpS12 (hkCP)	Ribosomal protein gene 12	Housekeeping
eEF1delta	Eukaryotic translation elongation factor 1 delta	Housekeeping
NipB	Cohesin loader Nipped-B	Housekeeping
X16	Putative splicing factor x16	Housekeeping
DSCP (dCP)	Derived from the even-skipped transcription factor	Developmental
pnr	Derived from the pannier transcription factor	Developmental

References

Zabidi MA, Arnold CD, Schernhuber K, Pagani M, Rath M, Frank O, Stark A. Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. Nature. 2015 Feb 26;518(7540):556-9.

Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 2008;9(9):R137.